Breast Cancer News, Features & Updates
From Crisis to Calling
- FDA Approves Tukysa Maintenance Treatment for HER2-Positive Metastatic Breast Cancer
October 8, 2026 — The FDA has approved Tukysa (tucatinib) combined with trastuzumab and pertuzumab for the maintenance treatment of adult patients with unresectable locally advanced or metastatic HER2-positive breast cancer after induction treatment.
- FDA Approves Etcamah Combination for Advanced Breast Cancer
September 8, 2026 — The FDA has approved Etcamah (camizestrant) in combination with a CDK4/6 inhibitor for the treatment of adult patients with HR-positive, HER2-negative advanced or metastatic breast cancer with an ESR1 mutation.
- SERD Elacestrant (Orserdu) for Breast Cancer: Expert Insights, Key Facts
An expert explains who may benefit from elacestrant (Orserdu), how this oral SERD works, its side effects, and what to expect.
- SERD Imlunestrant (Inluriyo) for Breast Cancer: Expert Insights, Key Facts
An expert explains who may benefit from imlunestrant (Inluriyo), how this oral SERD works, its side effects, and what treatment involves.
- Peer to Peer: Finding Your Early Breast Cancer Community
Two young women chat about the importance of finding community when you’re diagnosed with early breast cancer.
- Peer to Peer: Working With Early Breast Cancer
Two early breast cancer survivors share what helped them manage work, medical leave, finances, and returning to the job after treatment.
- The Power of Being Seen
Through breast cancer, Robin Roberts learned the value of self-advocacy, support, and trusting her instincts.
- FDA Approves Revtorpyk to Help Treat Certain Form Advanced Breast Cancer
July 15, 2026 — The FDA has approved Revtorpyk (gedatolisib) for the treatment of adults with HR-positive, HER2-negative advanced or metastatic breast cancer without a PIK3CA mutation.
- Ibrance: FDA Approves Oral Targeted Therapy With Anti‑HER2 and Endocrine Therapy for HR+, HER2+ Locally Advanced or Metastatic Breast Cancer
June 26, 2026 — The FDA has approved Ibrance (palbociclib) combined with trastuzumab, with or without pertuzumab, plus endocrine therapy as ongoing maintenance treatment for adults with hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-positive locally advanced or metastatic breast cancer whose disease is controlled after induction therapy with a taxane and anti‑HER2 therapy.
- Trodelvy (sacituzumab govitecan-hziy): First-Line Treatment for Triple-Negative Breast Cancer and an Antibody-Drug Conjugate Option for Certain Advanced Breast Cancers
June 25, 2026 — The FDA has approved sacituzumab govitecan-hziy (Trodelvy) to treat adults with certain types of triple-negative breast cancer (TNBC) who are not candidates for PD-1 or PD-L1 inhibitor-based therapy and, in combination with pembrolizumab (Keytruda) or pembrolizumab and berahyaluronidase alfa-pmph (Keytruda Qlex), to treat adults with unresectable locally advanced or metastatic TNBC whose tumors express PD-L1.
- Datroway: FDA Approves Antibody-Drug Conjugate Injection for Advanced Triple-Negative Breast Cancer
May 26, 2026 — The FDA has approved Datroway (datopotamab deruxtecan-dlnk), a TROP2-directed antibody-drug conjugate, for first-line treatment of unresectable or metastatic triple-negative breast cancer in adults who are not eligible for PD-1/PD-L1 immunotherapy.
- Enhertu: FDA Clears New Pre- and Post-Surgery Uses in HER2-Positive Early Breast Cancer
May 18, 2026 — The FDA has cleared new neoadjuvant and adjuvant uses for Enhertu (fam-trastuzumab deruxtecan-nxki) in adults with HER2-positive early breast cancer, positioning the medicine earlier in care.
- Veppanu (Vepdegestrant): An Oral Protein Degrader for Certain ER+/HER2- Advanced Breast Cancers
May 4, 2026 — The FDA approved Veppanu (vepdegestrant) for the treatment of adults with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-), estrogen receptor 1 (ESR1)-mutated advanced or metastatic breast cancer, with disease progression following at least one line of endocrine therapy and as detected by an FDA-authorized test. It is the first time the FDA has approved a proteolysis targeting chimera (PROTAC), a type of heterobifunctional protein degrader therapy.
- From Nausea to Insomnia: What Medical Cannabis Might (And Might Not) Help With During Breast Cancer Treatment
If you want to try cannabis for some extra relief from HR+/HER2- breast cancer symptoms and treatment side effects, you should know what it can and can’t do and what the risks may be for someone living with breast cancer.
- Enhertu Plus Pertuzumab: New First-Line Option for Advanced HER2-Positive Metastatic Breast Cancer
December 17, 2025 — Enhertu (fam-trastuzumab deruxtecan-nxki) is a type of targeted cancer treatment called an antibody-drug conjugate. The FDA has approved it in combination with another medicine, pertuzumab, as the first-line treatment for adults with HER2-positive breast cancer that has spread (metastatic) or cannot be removed with surgery (unresectable).
- ESR1 Mutations and Metastatic Breast Cancer
If you have estrogen receptor-positive breast cancer, you may develop an ESR1 mutation at some point. Find out what they are, and learn about promising new treatments.
- The Hopes and Unknowns of Clinical Trials
If you’ve been diagnosed with stage two or stage three breast cancer, a clinical trial is a great way to ensure you get cutting-edge treatment. Here’s what you need to know.
- How Different Treatments Work Together to Treat HR+/HER2- mBC
Treating HR+/HER2-negative metastatic breast cancer typically involves more than one treatment at a time. Find out what these combinations are and how your doctor chooses them.
- Factors That Determine the Course of Treatment for HR+/HER2- Metastatic Breast Cancer
What do doctors take into consideration when deciding on a course of treatment for HR+/HER2- metastatic breast cancer?
- Exercise: A New Breast Cancer 'Drug'?
Learn how exercise may help lower the chances of your breast cancer returning.
- Equal Access to Treatment May Improve Care for Minorities
For many women of color, accessing timely breast cancer care involves overcoming hurdles that complicate their treatment.
- I Have Breast Cancer. Here’s What I Told My Boss.
Breast cancer at work: How to handle whether or not to tell your boss, co-workers, and human resources department about your breast cancer diagnosis.
- Trusting Your Gut: Why Intuition Matters
Ignoring your instincts could cost you in the long run. Three women share their stories.
- Inluriyo: FDA Approves New Once-Daily Pill for ESR1-Mutated Advanced Breast Cancer in Patients Previously on Hormone Therapy
September 26, 2025 — The FDA approves Inluriyo (imlunestrant), a new oral treatment for people whose locally advanced or metastatic breast cancer is ER-positive, HER2-negative, and has a faulty ESR1 gene.
- How to Make Hard Choices Under Pressure After Breast Cancer Diagnosis
Learn how to make informed breast cancer treatment decisions with limited time. Get expert guidance on diagnosis, options, and next steps.
- Side Effect Anxiety: How to Manage Your Expectations and Your Reality
It’s human nature to have anxiety about side effects from breast cancer treatments. New approaches and solid support will help you through.
- Recurrence Risk vs. Tamoxifen Side Effects
Tamoxifen’s strong side effects can overwhelm. Explore why some women consider quitting and what you might do instead.
- These Women Had Differing Second Opinions About Their Breast Cancer Treatment. Here’s What They Did.
Are you considering a second opinion for your breast cancer treatment? Find out what others did.
- Paying for Breast Cancer Treatment: Costs and What to Expect
Out of any cancer, breast cancer has the highest treatment costs, and figuring out how to pay for treatment can be stressful and overwhelming. Learn how you can take steps to pay for treatment — with or without health insurance.
- I'm an Oncologist. Here Are Some Tips and Treatments That Can Help Reduce the Risk of Breast Cancer Recurrence
Here’s what an oncologist gives for tips and treatments to reduce breast cancer recurrence.
- How to Update Friends Without Feeling Overwhelmed
What do you tell your friends and family about your breast cancer diagnosis? Learn some tips on what to say and when to say it.
- Molecular Diagnostics: How Gene Tests Can Help Guide Your Breast Cancer Treatment Plan
You want the most effective treatment for your breast cancer. Learn how molecular diagnostics can guide your doctors toward a treatment that works best for your tumor.
- You’ve Done This Before: Leveraging Your Past Experiences
Your doctor says there's a high risk your cancer will come back. Find out ways to boost your defenses, and how to lean on your past experience if recurrence does happen.
- Breast Changes After Breast Cancer Treatment: What's Normal, What's Worth Checking, and What are the Red Flags?
Breast changes after cancer treatment are normal. Here’s what you may see after surgery or radiation, and when to see your doctor about breast changes.
- From Nausea to Insomnia: What Medical Cannabis Might (And Might Not) Help With During Breast Cancer Treatment
If you want to try cannabis for some extra relief from HR+/HER2- breast cancer symptoms and treatment side effects, you should know what it can and can’t do and what the risks may be for someone living with breast cancer.
- Sticking With Endocrine Therapy for the Long Haul: What It’s Like and Why It Matters
If you have hormone positive breast cancer, you’re likely a candidate for endocrine therapy. Here’s what you need to know about this type of treatment.
- Getting Through a Mastectomy, Step by Step
What can you expect before, during, and after your mastectomy? Get practical advice on your surgery, including what to bring to the hospital, what to have on hand at home, and more.
- How GLP-1 Drugs and Other Factors Impact Breast Cancer Recurrence
How do diet, alcohol, obesity, and other factors affect your chances of breast cancer recurrence? Oncologist Jane Meisel, MD, discusses best practices for lowering risk.
- Breast Cancer Treatment Side Effects: What Helps?
Breast cancer treatments are life saving, but they often come with their own challenging side effects. Oncologist Jane Meisel, MD, offers advice for managing the most common issues.
- Your Early-Stage Breast Cancer Questions, Answered
Two oncologists answer the most common early-stage breast cancer questions in this breast cancer Reddit AMA.
- Mastectomy or Lumpectomy? Reassuring New Data for Young Women
July 23, 2025 — For women under 40, breast cancer recurrence risk may be lower than previous estimates suggested. And new research supports patient choice for surgical treatment.
- Opting Out of Breast Cancer Treatment
New research is showing that some people who have breast cancer may not need as much treatment as once thought. Learn more from the ASCO Annual Meeting.
- The Hidden Side Effect of Cancer: Financial Toxicity
The cost of having cancer can ruin your finances. And it’s not just the treatments. An ASCO panel addressed financial toxicity.
- Follow-Up Care After Treatment for Primary Breast Cancer
Researchers at the ASCO meeting presented on top issues that affect breast cancer survivors. Learn about the importance of follow-up care.
- Dense Breast Tissue Can Hide Cancer. Now What?
June 11, 2025 — At least 4 out of 10 women have dense breast tissue and may need testing beyond a standard mammogram. Two new studies help clarify your next steps.
- Your Breast Cancer Risk May Have Just Changed – What to Know
April 1, 2025 — U.S. breast cancer deaths are no longer decreasing in women younger than 40, older than 74, or of Asian, Hispanic, or Native American descent. Experts share what they think is behind these and other disparities.
- Why Surgery May Not Be Needed for Low-Risk Breast Cancer
March 4, 2025 — A lumpectomy plus radiation is very effective for treating stage zero cancer, but new research suggests that active monitoring may be just as good.
- FDA Approves Drug for Hard-to-Treat Breast Cancer
January 28, 2025 — The FDA has approved fam-trastuzumab deruxtecan, marketed under the brand name Enhertu, as a new treatment for certain types of advanced breast cancer that have spread or cannot be removed with surgery.
- FDA Approves New Treatment for Advanced Breast Cancer
January 21, 2025 — The FDA has approved a new treatment for patients with a common form of breast cancer that has spread to other parts of the body or cannot be surgically removed.
