If you have diffuse large B-cell lymphoma (DLBCL) that either hasn't gotten better with treatment (refractory), or that went away for a while and then came back (relapsed), it can be hard to decide what to do next. There's no single treatment that works best for everyone, and the choices are complicated.
Immunomodulators work with your immune system to fight the cancer, by either holding back or encouraging the activity of certain immune cells.
What Are Immunomodulators for Relapsed and Refractory DLBCL?
Some medications can be part of the first treatment you get. Others will only be prescribed after you've tried other therapies.
Several types of immunomodulatory drugs are used to treat relapsed and refractory DLBCL.
What Are Direct B-Cell Cytolytics?
Direct B-cell cytolytics are drugs that look for and attach to cancer cells, causing their destruction.
Learn more about direct B-cell cytolytics.
What Are Antibody-Drug Conjugates?
Antibody-drug conjugates (ADCs) are medications that help chemotherapy drugs reach cancer cells more directly, so they do less damage to healthy cells.
Learn more about antibody-drug conjugates (ADCs).
What Is CAR T-Cell Therapy?
Chimeric antigen receptor (CAR) T-cell therapy is a type of treatment that teaches your immune system to attack the cancer cells.
Learn more about chimeric antigen receptor (CAR) T-cell therapy.
Bispecific T-Cell Engagers
Bispecific T-cell engagers (BiTEs) are drugs that connect cancerous B cells with infection-fighting T cells.
Learn more about bispecific T-cell engagers (BiTEs).
Making a Treatment Decision
While your doctor will recommend a treatment plan, it's important for you to understand all the options so you can take part in the decisions about your cancer care. Here are five things to keep in mind.