Digestive Disorders News, Features & Updates
- Palynziq (pegvaliase-pqpz): FDA Expands Enzyme Substitution Therapy to Adolescents 12+ With PKU to Help Lower Phenylalanine
March 3, 2026 — The FDA has expanded who can use Palynziq. It now includes adolescents 12 years and older with PKU whose Phe levels stay high despite care.
- Living With Phenylketonuria
Phenylketonuria (PKU) is a rare genetic disease that leads to developmental delays if untreated. See how one mom and her son, who has PKU, manage day to day.
- Expert Q&A: A Doctor's Experience With Phenylketonuria
Jerry Vockley, MD, PhD, chief of medical genetics and director of the Center for Rare Disease Therapy at the University of Pittsburgh Medical Center Children's Hospital of Pittsburgh, answers other common questions you might have about phenylketonuria (PKU).
- Recent Advances in Phenylketonuria
Since there's no cure for phenylketonuria (PKU), you'll need treatment throughout your life. But advances in specialty foods and new diagnostics have improved the outlook for people with this rare disease.
- Nereus: FDA Approves New Pill to Help With Motion Sickness
January 2, 2026 — Nereus (tradipitant) has become the first new prescription medicine for motion sickness approved by the FDA in more than 40 years.
- My Life With Primary Biliary Cholangitis (PBC)
Jess Harper recounts her journey from unexplained symptoms to diagnosis of primary biliary cholangitis (PBC) to managing her disease to how her life has changed with PBC.
- Recent Advances in Primary Biliary Cholangitis
Primary biliary cholangitis is a lifelong condition, but new treatments make the condition more manageable. Here's a look at recent advances.
- Expert Q&A: Primary Biliary Cholangitis
This rare liver disease is often overlooked. We asked an expert to share his insights on the disease, plus the challenges and exciting new treatments available.
- New Oral Treatment for Adults and Children With Phenylketonuria: Sephience
July 29, 2025 — Sephience (sepiapterin) is a new oral medication approved by the FDA to treat a rare inherited condition known as phenylketonuria (PKU) in adults and children aged 1 month or older.
- Coffee Drinkers Rejoice: Java May Boost Your Gut Health
A new study links coffee with better gut health (as if coffee lovers needed another reason to drink it).
- FDA OKs New Antibiotic Combo for Serious Abdominal Infections
February 10, 2025 — The FDA has approved a new antibiotic combination called Emblaveo to treat serious stomach infections in adults who have few or no other treatment options.
- How the Future of Medicine Will Revolve Around Our Gut
September 23, 2024 — Someday soon, your medicine cabinet will have pills not just for you, but also for the microbes in your gut.
- Pooping More Than This (or Less) Could Raise Disease Risk
July 18, 2024 — Bowel frequency can impact how your gut bacteria break down food, leading to byproducts that could harm your health over time, according to a new study.
- Are Direct-to-Consumer Microbiome Tests Useful? Probably Not
April 24, 2024 — Some companies claim they can identify and treat gastrointestinal problems with proprietary technology and products — experts disagree.
- How Soybean Oil Could Lead to Gut Inflammation
August 2, 2023 — Eating too much soybean oil, widely used in processed foods, could drive conditions like inflammatory bowel disease and leaky gut.
- Docs Steer Camera Through Stomach 'Like a Little Mars Rover'
June 23, 2023 — New magnetic tech allows doctors to perform guided endoscopy to detect gastric illnesses much earlier.
- Sucralose Damages DNA, Linked to Leaky Gut: Study
June 1, 2023 — A new study reveals health concerns about the sugar substitute sucralose so alarming that researchers said people should stop eating it and the government should regulate it more.
- New Fecal Transplant Pill Approved to Restore Gut Flora
April 27, 2023 — People with the painful and often recurring form of the bacterial infection known as C. diff can now take a helpful treatment called fecal transplant therapy by simply swallowing a pill.
- COVID Increases Risk of Long-Term GI Troubles: Study
March 8, 2023 — People who have had COVID-19 have a higher risk of developing new, long-term digestive problems, according to a study published Tuesday in the journal Nature Communications.
- Swallow This: Tiny Tech Tracks Your Gut in Real Time
February 28, 2023 — A new pill-like device could help diagnose GI issues with greater comfort and ease than current tests.
- Drug-Resistant Stomach Bug Infections on the Rise: CDC
February 27, 2023 — Health officials are warning that an increase in the drug-resistant form of the bacteria shigella is a “serious public health threat.”
- Vibrating Pill Can Help Treat Constipation
February 9, 2023 — A new vibrating pill shown to help relieve constipation is now available.
- The Social Aspects of Living With Eosinophilic Esophagitis
Ryan Piansky has had eosinophilic esophagitis since he was 2 years old. Learn more about how he’s learned to navigate his social life with the condition.
- What Are Postbiotics?
Postbiotics are part of your body's microbiome, the collection of microorganisms that keep you healthy. Learn more about what they are, why they're important, and more.
- Best Bets for Beating Gas
Gas can be uncomfortable and embarrassing, but you can squelch it by changing your diet.
- The Truth About Gas
Many people don’t know much about intestinal gas, even though we all have it. It’s time to take the air out of some of the myths behind flatulence and belching.
- Foods That Fight Heartburn
You know certain foods can give you heartburn. But did you know others can help control it?
- Aging and Digestive Health
Learn how aging affects your digestive health and get tips to promote good digestion.
- Leaky Gut Syndrome: What Is It?
Leaky gut syndrome is not a diagnosis taught in medical school, but instead points to a group of common symptoms that has not yet lead to a diagnosis. WebMD discusses what these symptoms mean and how increasing research might lead to a better understanding of this illness.
- Lactose: How Much Can You Take?
Are you lactose intolerant and unsure about how much lactose you can have? Get the facts here.
- Lactose-Free Milk and Nondairy Beverages
If you're lactose intolerant, you can still enjoy light coffee and creamy desserts with nondairy and lactose-free options instead of milk.
- School Germs and Your Child’s Health
In winter, schools are transformed into hothouses for germs, exposing children to an onslaught of viruses. Here’s how to help your child cope with colds, flu, and stomach bugs during the school year.
- Seasonal Digestive Distress: 10 Tips for Coping
Do barbecues and fair food give you stomachaches or diarrhea? Manage digestive problems with tips from the pros.
- Bloating 101: Why You Feel Bloated
Bloating and gas are usually tied to what and how you eat, so a few simple changes may ease your discomfort.
- Preventing Dehydration When You Have Diarrhea or Vomiting
A prolonged bout of diarrhea or vomiting can cause the body to lose more fluid than it can take in, resulting in dangerous dehydration.
- Gallbladder Diet
Experts discuss foods that are good for your gallbladder, as well as what not to eat when you have gallbladder problems.
- Top Digestive Health Stories of 2008: Readers' Choice
Your stomach. You can’t live without it, but why does it cause you so much trouble? Readers who wanted to know made this the top story of 2008.
- Secrets to Gas Control
Gas can often accompany diarrhea, making an uncomfortable situation even worse. Here’s how to make your GI tract behave better.
- Living with GERD and Food Intolerances: Trudy McCulloch's Story
How one WebMD community member discovered -- and learned to cope with – GERD and food intolerances.
- Get Help for Your Hemorrhoids
You aren't the first person -- and you won't be the last -- to have hemorrhoids. You don't have to suffer. Get tips from an expert and someone who's been there.
- Chronic Constipation: Facts vs. Myths
Chronic constipation is a common problem that can often be relieved by following a multifaceted lifestyle approach to treatment.
- Tip Sheet: Ulcers and Pain Relievers
People with ulcers must use caution when taking over-the-counter pain relief medications. Follow these tips to be safe.
- Gas, Bloating: Always Uncomfortable?
Upset stomach got you down? Gas, bloating, and bathroom problems are a constant battle for many people -- often the symptoms are related to diet, but there are some more serious medical conditions that may be the culprit.