Overview: Pulsatilla is a plant in the Ranunculaceae (buttercup) family. It is available over-the-counter as an herbal supplement and as a homeopathic remedy. Pulsatilla is commonly used for various reasons, including colds, ear infections, menstrual complaints, and digestive issues, but its benefits are not well defined. The fresh plant contains a chemical called protoanemonin, which can irritate the skin, mouth, and stomach. Before taking pulsatilla, make sure to tell your health care provider about any health conditions you have or medicines you are taking.
Uses
What is pulsatilla used for?
Pulsatilla (Pulsatilla chinensis, Pulsatilla pratensis, Pulsatilla vulgaris) is used for a variety of reasons. Its benefits for any use are not well defined. Some reasons that people may take pulsatilla include the following.
- Infections
- Menstrual problems
- Digestive problems
Note: The FDA has not reviewed pulsatilla for safety and effectiveness. Learn more about dietary supplements here.
How does pulsatilla work (mechanism of action)?
Pulsatilla is a flowering plant in the Ranunculaceae (buttercup) family. Several species of pulsatilla are used in herbal and homeopathic products, including Pulsatilla vulgaris (also called pasque flower), Pulsatilla pratensis (also called small pasque flower or Pulsatilla nigricans), and Pulsatilla chinensis (also called bai tou weng in traditional Chinese medicine). These plants are native to Europe and parts of Asia.
Pulsatilla is available in two main forms:
- Herbal supplements. These are made from parts of the pulsatilla plant, such as the dried aerial parts (the parts of the plant that grow above the ground). Herbal pulsatilla products include tinctures, liquid extracts, dried powders, and teas.
- Homeopathic products. These are made by repeatedly diluting a substance from the pulsatilla plant in water or alcohol. Homeopathic pulsatilla products are usually available as small pellets, tablets, or liquid drops. Because homeopathic products are very dilute, they contain very little or none of the original plant material.
The fresh pulsatilla plant contains chemicals called ranunculin, protoanemonin, saponins, and flavonoids. When the plant is dried or processed, protoanemonin converts into another chemical called anemonin. Lab studies have shown that anemonin may have antipyretic (fever-reducing) and sedating effects. Saponins may contribute to the anti-inflammatory effects. However, these effects have not been confirmed in humans, and the benefits of pulsatilla for any use are not well defined.
Herbal products, such as pulsatilla, naturally contain many different chemicals, including protoanemonin, anemonin, saponins, and flavonoids. The amounts of each chemical in a specific pulsatilla product may vary. Some, none, or all of these chemicals may have effects on the body. These effects may change depending on how much of each chemical is found in the product you are using.
How should I store pulsatilla?
You should store pulsatilla according to the product label. Most dietary supplements should be kept in a cool, dry location that is out of the reach of children and pets and not in direct sunlight.
Side Effects
What are the most common side effects of pulsatilla?
There is not enough research to know what the common side effects of pulsatilla may be. Tell your health care provider if you have any side effects that bother you.
There may be side effects of pulsatilla that are not listed here. Contact your health care provider if you think you are having a side effect of a supplement. In the U.S., you can report side effects to the FDA at www.safetyreporting.hhs.gov or by calling 888-SAFEFOOD (888-723-3366). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.
What are the serious side effects of pulsatilla?
While less common, the most serious side effects of pulsatilla are described below, along with what to do if they happen.
Severe Allergic Reactions. Pulsatilla may cause allergic reactions, which can be serious. Stop taking pulsatilla and get help right away if you have any of the following symptoms of a serious allergic reaction.
- Breathing problems or wheezing
- Racing heart
- Fever or general ill feeling
- Swollen lymph nodes
- Swelling of the face, lips, mouth, tongue, or throat
- Trouble swallowing or throat tightness
- Itching or skin rash
- Bumps on the skin called hives that can be red, pink, white, or brown depending on your skin tone
- Nausea or vomiting
- Dizziness, feeling lightheaded, or fainting
- Stomach cramps
- Joint pain
Skin Irritation From the Fresh Plant. The fresh pulsatilla plant contains a chemical called protoanemonin that can cause blistering and irritation of the skin if touched. Do not handle the fresh plant with bare hands. Dried or processed pulsatilla products contain much less protoanemonin and may be less likely to cause skin irritation. If you develop blisters, redness, or severe skin irritation after contact with pulsatilla, wash the area with soap and water. Contact your health care provider if you have skin irritation that bothers you after contact with pulsatilla.
Warnings & Precautions
Who should not use pulsatilla?
Allergies to Ingredients. People who are allergic to any of the following should not take pulsatilla.
- Pasque flower
- Pulsatilla
- Pulsatilla chinensis
- Pulsatilla nigricans
- Pulsatilla pratensis
- Pulsatilla vulgaris
- Any of the ingredients in the specific product
Your pharmacist can tell you all of the ingredients in the specific pulsatilla products they stock.
What should I know about pulsatilla before using it?
Pulsatilla is available as a dietary supplement and a homeopathic product. It cannot be marketed to treat or cure a disease.
Read and follow the directions on the specific product you are taking, or take it as recommended by your health care provider.
Keep pulsatilla out of the reach of children.
The fresh pulsatilla plant is toxic and should not be eaten, touched with bare hands, or applied to the skin. It contains a chemical called protoanemonin that can cause blistering of the skin and severe irritation of the mouth, throat, and stomach. Only dried or properly processed pulsatilla products should be used. Drying and processing the plant converts protoanemonin into anemonin, which is considered less harmful.
Pulsatilla is available both as an herbal supplement and a homeopathic remedy. These are different types of products. Herbal pulsatilla products contain measurable amounts of plant chemicals and may cause side effects. Homeopathic pulsatilla products are extremely diluted and contain very little or none of the original plant material. Make sure you know which type of product you are using, and read the product label carefully.
Herbal products, such as pulsatilla, naturally contain many different chemicals. The amount of each chemical in a specific pulsatilla product can change for many reasons, including the species of pulsatilla used, the part of the plant used, the area where the plant was grown, the weather during growth, the time of year when it was harvested, and the way the plant was processed after being harvested. If you switch to a new bottle or a different brand, you may not have the same effects or side effects because of this variability. Talk to your health care provider if you have questions or concerns.
Pulsatilla products may be made from different parts of the plant. For example, some products are made from the root, while others are made from the aerial parts (the parts of the plant that grow above the ground), such as the flowers, leaves, or stems. Each of these plant parts contains different chemicals that may have different effects on the body. It is important to read the product label to confirm which part of the plant was used to make that product.
Pulsatilla is available in many different forms, including herbal tinctures, liquid extracts, dried ground powder, teas, and homeopathic pellets or drops. Each of these forms may contain different amounts of the chemicals naturally found in the plant.
If you are using pulsatilla liquid extract or tincture, use an accurate measuring device to measure your dose. A household spoon is not an accurate measuring device and may cause you to take the wrong dose. Read the product label carefully, and follow the instructions on the label.
The FDA has not tested pulsatilla products to confirm that they contain the ingredients stated on their labels. Some dietary supplements have been tested by third-party organizations to confirm that they contain the ingredients listed on their labels and do not contain any harmful chemicals. Learn more about how to choose a safe dietary supplement product here.
What should I tell my health care provider before using pulsatilla?
Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if pulsatilla is right for you.
In particular, make sure that you discuss any of the following.
Allergies to Certain Plants. If you are allergic to any plants in the Ranunculaceae (buttercup) family, such as buttercups, clematis, or anemone, you may also be allergic to pulsatilla. Tell your health care provider about any plant allergies you have before taking pulsatilla.
Current and Past Health Conditions. Tell your health care provider if you have any of the following.
- Kidney problems
- Liver problems
Pregnancy. Pulsatilla may cause harm to a fetus. You should not take pulsatilla if you are pregnant. Tell your health care provider if you are pregnant or plan to become pregnant.
Breastfeeding. It is not known if pulsatilla passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed.
Interactions
Does pulsatilla interact with foods or drinks?
There are no known interactions between pulsatilla and foods or drinks.
It is unknown if drinking alcohol will affect pulsatilla.
Does pulsatilla interact with medicines (drug interactions)?
Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
The interactions between pulsatilla and medicines are not fully understood. As with most dietary supplements, the research on drug interactions with pulsatilla is incomplete. Always check with your health care provider before taking pulsatilla with any medicines.
Overdose/Missed Dose
What should I do if I accidentally use too much pulsatilla?
If you or someone else has used too much pulsatilla, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.
The fresh pulsatilla plant is toxic and should not be eaten or touched with bare hands. Only dried or properly processed pulsatilla products should be used. Read the product label closely, and speak to your health care provider about how to use pulsatilla safely. Do not take double or extra doses, even if you miss a dose.
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