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Overview: Goat's rue is an herbal product made from the flowering parts of a plant called Galega officinalis. People take goat's rue to help lower blood sugar, manage weight, and increase breast milk, but its benefits are not well defined. Goat's rue has not been well studied in people, so its common side effects are not known. Before taking goat's rue, tell your health care provider about any health conditions you have and any medicines you take.

Uses

What is goat's rue used for?

Goat's rue (Galega officinalis) is an herbal product made from parts of a plant in the pea family. The benefits of goat's rue are not well defined. It has been used for the following reasons.

Note: The Food and Drug Administration (FDA) has not reviewed goat's rue for safety and effectiveness, and it is not approved by the FDA. Learn more about dietary supplements here.

How does goat's rue work (mechanism of action)?

Goat's rue is an herbal product. It is made from the leaves and flowering aboveground parts of a plant called Galega officinalis, which is in the pea (legume) family. The plant is also known by names such as French lilac and Italian fitch.

Goat's rue naturally contains chemicals called guanidine derivatives. The main one is called galegine. Galegine and similar chemicals are thought to help lower blood sugar. Research suggests that goat's rue chemicals may help the body move sugar out of the blood and into muscle, and may lower the amount of sugar made by the body. In animal studies, galegine has also been linked to weight loss and eating less food. Long ago, the study of guanidine chemicals from goat's rue was part of the early research that led to the diabetes medicine metformin. But goat's rue itself has mostly been studied in animals, not people. These benefits are not well defined.

Goat's rue has been studied in mice for weight loss and to lower food intake. These benefits are not well defined, and this has not been shown in people.

Goat's rue has traditionally been used by breastfeeding parents to try to make more breast milk. It is a well-known herbal galactagogue, which is a product used to try to boost milk supply. But it has not been well studied. High-quality studies are lacking, and research reviews have had to leave out studies of this use because they were poorly done. The only sign of more milk came from products that mixed goat's rue with other ingredients, not from goat's rue by itself. The evidence for even that was weak. The benefits of goat's rue for making more breast milk are not well defined.

It is not well understood how or whether goat's rue works for any health condition in people. Evidence in humans is limited.

Herbal products, such as goat's rue, naturally contain many different chemicals. The amounts of each chemical in a specific goat's rue product may vary. Some, none, or all of these chemicals may have effects on the body. These effects may change depending on how much of each chemical is found in the product you are using.

How should I store goat's rue?

You should store goat's rue according to the product label. Most dietary supplements should be kept in a cool, dry location that is out of the reach of children and pets and not in direct sunlight.

Side Effects

What are the most common side effects of goat's rue?

There is not enough research to know what the common side effects of goat’s rue may be. Tell your health care provider if you have any side effects that bother you.

Goat's rue contains a natural chemical called galegine that may lower blood sugar. Hence, goat's rue may cause low blood sugar (hypoglycemia). This may be more likely if you have diabetes or take medicines that lower blood sugar.

There may be side effects of goat's rue that are not listed here. Contact your health care provider if you think you are having a side effect of a supplement. In the U.S., you can report side effects to the FDA at www.safetyreporting.hhs.gov or by calling 888-SAFEFOOD (888-723-3366). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of goat's rue?

While less common, the most serious side effects of goat's rue are described below, along with what to do if they happen.

Severe Allergic Reactions. Goat's rue may cause allergic reactions, which can be serious. Stop taking goat's rue and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching or skin rash
  • Bumps on the skin called hives that can be red, pink, white, or brown depending on your skin tone
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Low Blood Sugar (Hypoglycemia). Goat's rue contains galegine and similar chemicals that may lower blood sugar. It may rarely lead to low blood sugar. This is more likely if you have diabetes or take medicines that lower blood sugar. Very low blood sugar can be serious. You may need to check your blood sugar more often if you make changes to your diet, exercise regimen, or medicines for diabetes. Do not use goat's rue and call your health care provider right away if you have any of the following symptoms of hypoglycemia.

  • Headache
  • Crankiness or anxiety
  • Hunger
  • Dizziness or confusion
  • Blurry vision
  • Slurred speech
  • Sweating
  • Feeling jittery or shakiness
  • Fast heartbeat
  • Seizures

Warnings & Precautions

Who should not use goat's rue?

Allergies to Ingredients. People who are allergic to any of the following should not take goat's rue.

  • French lilac
  • Galega officinalis
  • Goat's rue
  • Italian fitch
  • Professor-weed
  • Any of the ingredients in the specific product

Your pharmacist can tell you all of the ingredients in the specific goat's rue products they stock.

What should I know about goat's rue before using it?

Goat's rue is a dietary supplement. It cannot be marketed to treat or cure a disease.

Goat's rue is available in several forms. Common forms include capsules, dried herb used to make tea, and liquid extracts (tinctures). It may also be found in combination products that contain other herbs or supplements. Read and follow the directions on the specific product you are taking, or take it as recommended by your health care provider.

Keep goat's rue out of the reach of children.

The raw goat's rue plant can be toxic. The plant can poison grazing animals, such as sheep, if they eat it in large amounts. So, do not eat the raw plant. Use only properly made goat's rue products, and follow the directions on the label.

Goat's rue is not the same as the prescription diabetes medicine metformin. Long ago, scientists studied a natural chemical in goat's rue called galegine. This early work helped lead to the discovery of metformin. But goat's rue is an herbal supplement, not a tested medicine. It is not approved to treat diabetes, and the amount of active chemical in a goat’s rue product can vary. Do not use goat's rue in place of a medicine your health care provider has prescribed.

Herbal products, such as goat's rue, naturally contain many different chemicals. The amount of each chemical in a specific goat's rue product can change for many reasons, including the area where the plant was grown, the weather during growth, the time of year it was harvested, and the way it was processed after being harvested. If you switch to a new bottle or a different brand, you may not have the same effects or side effects because of this variability. Talk to your health care provider if you have questions or concerns.

Goat's rue is available in many different forms, including dried ground herb, tea, capsules, and liquid extracts. Each of these forms may contain different amounts of the chemicals that are naturally found in the plant.

The FDA has not tested goat's rue products to confirm that they contain the ingredients stated on their labels. Some dietary supplements have been tested by third-party organizations to confirm that they contain the ingredients listed on their labels and do not contain any harmful chemicals. Learn more about how to choose a safe dietary supplement product here.

What should I tell my health care provider before using goat's rue?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. Also tell them if you have an upcoming surgery planned. Sharing this information will help your health care provider know if this or other supplements are right for you.

In particular, make sure that you discuss any of the following.

Diabetes or Trouble With Low Blood Sugar. Goat's rue may lower blood sugar. Tell your health care provider if you have diabetes, low blood sugar, or any other condition that affects your blood sugar.

Other Medicines and Supplements. Before taking goat's rue, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Pregnancy. It is not known if or how goat's rue could affect pregnancy or harm a fetus. In general, many herbal products have not been shown to be safe during pregnancy. Tell your health care provider if you are pregnant or plan to become pregnant.

Breastfeeding. It is not known if goat's rue passes into breast milk. Goat's rue is sometimes used to try to increase breast milk, but it is not known if it is safe or useful for this purpose. There is not enough research on whether herbal supplements like goat's rue are safe while breastfeeding. There is a report about babies who had low energy, poor feeding, and vomiting after the parent drank an herbal tea mixture that contained several herbs, including goat's rue. If you use goat's rue while breastfeeding, watch your baby closely and talk to your health care provider first. Tell your health care provider if you are breastfeeding or plan to breastfeed.

Interactions

Does goat's rue interact with foods or drinks?

There is not enough research to know if goat's rue interacts with foods or drinks.

It is unknown if drinking alcohol will affect goat's rue. Goat's rue may lower blood sugar, and alcohol can also affect blood sugar. It is best to limit the amount of alcohol you drink.

Does goat's rue interact with medicines (drug interactions)?

Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using so they can watch for any potential interactions.

In particular, make sure that you discuss if you are using any medicine for diabetes, such as glipizide (Glucotrol), insulin, or metformin (Glucophage and others) before taking goat’s rue.

The interactions between goat's rue and medicines are not fully understood. As with most dietary supplements, the research on drug interactions with goat's rue is incomplete. Always check with your health care provider before taking goat's rue with any medicines.

Overdose/Missed Dose

What should I do if I accidentally use too much goat's rue?

If you or someone else has used too much goat's rue, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

Goat's rue is available in several forms, such as capsules, dried herb used to make tea, and liquid extracts. Do not take more than the amount listed on the product label. Read the product label closely and speak with a health care provider about how to use goat's rue safely. Do not take double or extra doses, even if you miss a dose.