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Overview: Trogarzo is used with other medicines to treat HIV. It prevents HIV from infecting certain immune cells in your body. Common side effects can include diarrhea, nausea, dizziness, and rash. Serious side effects are less common but may include changes to your immune system. Tell your health care provider right away if you have fever, sweats, chills, muscle aches, swollen lymph nodes, vision problems, confusion, or problems talking. Missing doses of any medicine for HIV can cause it to not work as well. It is important not to miss or skip Trogarzo doses.

Uses

What is Trogarzo used for?

Trogarzo (ibalizumab) is commonly used for the treatment of human immunodeficiency virus type-1 (HIV-1) infection.

Trogarzo may also be used for other conditions as determined by your health care provider.

How does Trogarzo work (mechanism of action)?

Trogarzo works by preventing HIV from infecting certain immune cells in your body called CD4-positive T cells. Thus, the amount of HIV in your body falls, which helps to control HIV infection.

How is Trogarzo supplied (dosage forms)?

Trogarzo is available in an injectable form.

How should I store Trogarzo?

Trogarzo is usually given by a health care provider in a hospital or clinic. If you will store Trogarzo at home, follow the instructions given by your health care provider.

Side Effects

What are the most common side effects of Trogarzo?

The most common side effects of Trogarzo are listed below. Tell your health care provider if you have any of these side effects that bother you.

  • Diarrhea
  • Dizziness
  • Nausea
  • Rash

There may be other side effects of Trogarzo that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Trogarzo?

While less common, the most serious side effects of Trogarzo are described below, along with what to do if they happen.

Severe Allergic Reactions. Trogarzo can cause allergic reactions, which can be serious. Stop using Trogarzo and get help right away if you have any of the following symptoms of a serious allergic reaction

  • Breathing problems or wheezing
  • Racing heart
  • Chest pain or tightness
  • Trouble swallowing or throat tightness
  • Itching or skin rash
  • Bumps on the skin called hives that can be red, pink, white, or brown depending on your skin tone
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Cough
  • Hot flushes
  • Nausea or vomiting
  • Swelling of the face, lips, mouth, tongue, or throat

Immune System Changes. When you start Trogarzo, your immune system might get stronger and start fighting infections that have been hiding inside your body for a long time. The type of symptoms you may have will depend on the infection. Tell your health care provider right away if you notice any of the following new symptoms of infection. 

  • Fever, sweats, chills, or muscle aches
  • Swollen lymph nodes
  • Vision problems
  • Confusion, problems talking, or headache
  • Skin problems such as a painful rash or warts
  • Cough or coughing up blood
  • Weakness or coordination problems 

Warnings & Precautions

Who should not use Trogarzo?

Allergies to Ingredients. People who are allergic to any of the following should not use Trogarzo.

  • Ibalizumab-Uiyk
  • Trogarzo
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Trogarzo.

What should I know about Trogarzo before using it?

Trogarzo is usually given by a health care provider in a hospital or clinic. 

Trogarzo can affect your alertness or coordination. Do not drive or do other activities that require alertness or coordination until you know how Trogarzo affects you.

What should I tell my health care provider before using Trogarzo?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Trogarzo is right for you.

In particular, make sure that you discuss any of the following.

Pregnancy. It is not known if or how Trogarzo could affect pregnancy or harm a fetus. Tell your health care provider if you are pregnant or plan to become pregnant. Your health care provider will let you know if you should use Trogarzo while you are pregnant or trying to get pregnant. The Antiretroviral Pregnancy Registry collects safety information about the use of antiretrovirals during pregnancy. Tell your health care provider if you are interested in participating.

Breastfeeding. You should not breastfeed if you have human immunodeficiency virus type 1 (HIV-1) because of the risk of passing it to your baby. It is not known if Trogarzo passes into breast milk. Talk with your health care provider about how to best feed your baby while you are using Trogarzo. 

How can I get more information about Trogarzo?

For more information about Trogarzo, you can visit the manufacturer’s website at https://www.TROGARZO.com or call them at 833-238-4372.

Interactions

Does Trogarzo interact with foods or drinks?

There are no known interactions between Trogarzo and foods or drinks.

It is unknown if drinking alcohol will affect Trogarzo. The risk of dizziness may be increased if you drink alcohol while using Trogarzo.

Does Trogarzo interact with other medicines (drug interactions)?

There are no known interactions between Trogarzo and other medicines. Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much Trogarzo?

If you or someone else has used too much Trogarzo, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of Trogarzo?

Missing doses of Trogarzo can cause it to not work as well over time. So it’s important not to miss or skip doses. If you miss an appointment to get your Trogarzo dose, call to make another appointment as soon as possible. Tell your health care provider right away if you stop Trogarzo or any other medicine for HIV.