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Overview: Ilumya is used for certain people with a skin condition known as plaque psoriasis. It reduces symptoms by affecting your immune system. Common side effects can include diarrhea or pain, itching, redness, or swelling where it is injected. Serious side effects are less common, but may include infections. Tell your health care provider right away if you think you have an infection. Before you start using Ilumya, talk to your health care provider about infections you have had and any vaccines you may need. 

Uses

What is Ilumya used for?

Ilumya (tildrakizumab-asmn) is commonly used to treat people with moderate to severe plaque psoriasis who may benefit from an injection, pill, or ultraviolet (UV) light therapy.

Ilumya may also be used for other conditions as determined by your health care provider.

How does Ilumya work (mechanism of action)?

Ilumya works by blocking the effect of a substance called interleukin-23 (IL-23). This substance is normally made by your body and is part of your body’s response to inflammation. Blocking this substance can help treat the symptoms of psoriasis.

How is Ilumya supplied (dosage forms)?

Ilumya is available in an injectable form.

How should I store Ilumya?

Store Ilumya in the original carton in a refrigerator, between 36 F and 46 F (2 C and 8 C). Do not freeze Ilumya. 

You can store Ilumya for up to 30 days at room temperature, between 68 F and 77 F (20 C and 25 C) in the original carton to protect it from light. 

Do not store Ilumya above 77 F (25 C). Throw Ilumya away after 30 days if kept at room temperature. If stored at room temperature for less than 30 days, do not place Ilumya back in the refrigerator. 

Side Effects

What are the most common side effects of Ilumya?

The most common side effects of Ilumya are listed below. Tell your health care provider if you have any of these side effects that bother you.

  • Infection in the nose or throat, sore throat, or common cold symptoms
  • Pain, itching, redness, or swelling at the injection site
  • Diarrhea

There may be other side effects of Ilumya that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Ilumya?

While less common, the most serious side effects of Ilumya are described below, along with what to do if they happen.

Severe Allergic Reactions. Ilumya can cause allergic reactions, which can be serious. Stop using Ilumya and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching or skin rash
  • Bumps on the skin called hives that can be red, pink, white, or brown depending on your skin tone
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Infection. Ilumya can increase the risk of infections, including serious infections. Call your health care provider if you have an infection or any of the following symptoms.

  • Burning or stinging when you pee 
  • Cough or coughing up blood
  • Fever, sweats, chills, or muscle aches
  • Shortness of breath
  • Diarrhea or stomach pain
  • Weight loss

Warnings & Precautions

Who should not use Ilumya?

Allergies to Ingredients. People who are allergic to any of the following should not use Ilumya.

  • Ilumya
  • Tildrakizumab-asmn 
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Ilumya.

What should I know about Ilumya before using it?

A health care provider will give you each dose of Ilumya. 

 

What should I tell my health care provider before using Ilumya?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Ilumya is right for you.

In particular, make sure that you discuss any of the following.

Infection. Tell your health care provider if you have an infection or an infection that keeps coming back. Also tell your health care provider if you have tuberculosis (TB), even if you are getting treatment, or if you live or work with someone who has TB. Your health care provider will likely check to see if you have TB before prescribing this medicine.

Vaccines. Talk with your health care provider about any vaccines that you may need. You should not receive certain vaccines right before or while using Ilumya. Tell your health care provider about any vaccines you have recently received or have scheduled.

Pregnancy. It is not known if or how Ilumya could affect pregnancy or harm a fetus. Tell your health care provider if you are pregnant or plan to become pregnant. Your health care provider will let you know if you should use Ilumya while you are pregnant or trying to get pregnant.  If you become pregnant while using Ilumya, you can sign up for the registry that collects information about anyone who is using Ilumya for plaque psoriasis and gets pregnant. You can sign up by calling 866-626-6847 or at mothertobaby.org/ongoingstudy/ilumya-tildrakizumab-asmn.
 

Breastfeeding. It is not known if Ilumya passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed. Your health care provider will let you know if you should use Ilumya while breastfeeding.

How can I get more information about Ilumya?

For more information about Ilumya, you can visit the drugmaker’s website at www.Ilumya.com or call them at 800-818-4555.

Interactions

Does Ilumya interact with foods or drinks?

There are no known interactions between Ilumya and foods or drinks.

It is unknown if drinking alcohol will affect Ilumya.

Does Ilumya interact with other medicines (drug interactions)?

There are no known interactions between Ilumya and other medicines. Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.  

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much Ilumya?

If you or someone else has used too much Ilumya, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of Ilumya?

Ilumya is usually given by a health care provider in a hospital or clinic. Your health care provider will make sure you are receiving Ilumya as scheduled. If you miss an appointment to get your dose, call to make another appointment as soon as possible.