Granix (Tbo-Filgrastim) - Uses, Side Effects, and More

Who should not use Granix?

Allergies to Ingredients. People who are allergic to any of the following should not use Granix.

• Filgrastim
• Granix
• Pegfilgrastim
• Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Granix.

What should I know about Granix before using it?

Do not use Granix unless it has been prescribed to you by a health care provider. Use it as prescribed. Only use Granix if your health care provider has trained you or your caregiver on how to use it. If you or your caregiver will be giving Granix at home, read and follow the instructions for use that come with your medicine. Talk to your pharmacist if you have any questions about how to use Granix. 

Do not skip doses, change your dose, or stop using Granix without talking about this with your health care provider. 

Do not share Granix with other people, even if they have the same condition as you. It may harm them.

Do not share needles or syringes with other people. Always use a new needle or syringe for each injection.

Keep Granix out of the reach of children. Since this medicine must be kept in a refrigerator, take special precautions to keep it away from children who also use the refrigerator.

Take Granix out of the refrigerator for 30 minutes before preparing your dose. After you inject your dose, throw away any unused Granix. 

Do not shake Granix. Do not inject where your skin is thickened or bruised.

Use Granix at least 24 hours before or 24 hours after chemotherapy. 

You will need to have your blood checked while using Granix. Keep all appointments to check your blood.

Bone pain is a common side effect of Granix. Talk to your health care provider about your options to safely treat this pain. They may recommend an over-the-counter pain medicine such as acetaminophen or a nonsteroidal anti-inflammatory drug. 

What should I tell my health care provider before using Granix?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Granix is right for you.

In particular, make sure that you discuss any of the following.

Breast or Lung Cancer. Granix may increase the risk of a type of cancer called acute myeloid leukemia (AML) or a condition called myelodysplastic syndrome in certain people. If you have breast cancer or lung cancer and use Granix with chemotherapy and/or radiation therapy, call your health care provider if you become more tired than usual, have easy bruising or bleeding, and fever.

Congenital Neutropenia. Granix may increase the risk of a type of cancer called acute myeloid leukemia (AML) or a condition called myelodysplastic syndrome in certain people. If you have congenital neutropenia, call your health care provider if you become more tired than usual, have easy bruising or bleeding, and fever.

Sickle Cell Disorder. Tell your health care provider if you have sickle cell disorder. Granix may cause a sickle cell crisis in people who have this condition. Call your health care provider and stop using Granix if you have symptoms such as pain or trouble breathing.

Current and Past Health Conditions. Tell your health care provider if you have any of the following.

• Kidney problems
• Receiving radiation therapy
• Upcoming bone scan or test

Pregnancy. It is not known if or how Granix could affect pregnancy or harm a fetus. You should avoid getting pregnant while using Granix. Tell your health care provider if you are pregnant or plan to become pregnant. 

Breastfeeding. It is not known if Granix passes into breast milk. You should avoid breastfeeding while using Granix and for 2 weeks after your last dose. 

How can I get more information about Granix?

For more information about Granix, you can visit the drugmaker’s website at www.granixrx.com or call them at 888-4-TEVARX (888-483-8279).