I have a post, back in October 2009, about my experience with Lialda. At the time I was wanting to know of alternative medications and other natural ways to treat my ulcerative colitis. I reduced my dosage of my Lialda, on my own, over the months of October and November and just stayed on the Canasa Suppositories at night. I experimented with Omega 3,6,9 oils, Aloe Vera Juice and probiotics. I also tried peppermint, wintergreen and spearmint essential oils. Flax oils. Eating lots of salmon ... and joined a group that only ate raw food. And started eating raw and eating no dairy or sugars. I did this through the months of December and January. IT DID NOT WORK. I started to flare Januray 22, 2010 and I experienced the worst flare I have ever experienced. I was going to the rest room up to 20 times a day. I experienced horrible stomach cramping, diarrhea that was pure liquid and LOTS of blood. I have lost 15 pounds in a month and am anemic. I went to my Gastro Dr.in February and am now on tons of medication to get me back into remission. At frist, I was back on 4 pills a day of the Lialda and Mesalamine Ennamas at night. I have been on this medication for a month now and saw a bit of relief after 3 weeks, but not a complete recovery. My Dr. last week also put me on 40mg of Predisone and I am starting to feel somewhat better. I am going to the bathroom up to 5 times a day and the blood is subsiding. I have missed a lot of work days and have used many sick calls. I now wish that 4 pills of Lialda was all I needed to take. Looking back now, I miss those days. All I have to suggest to everyone is to take your medication as the Dr. tells you. The Lialda did have some side effects but they are no way as bad as what you go though going off of it. Read More Read Less