Amiloride (Midamor) - Uses, Side Effects, and More

Who should not use amiloride?

Allergies to Ingredients. People who are allergic to any of the following should not take amiloride.

• Amiloride
• Midamor
• Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in the specific amiloride products they stock.

No Urine Production. Do not take amiloride if you are making very little to no pee. This condition is also called anuria.

Other Kidney Problems. Amiloride should not be taken if your kidneys are not working as well as they should be. If there is a concern about the health of your kidneys, your health care provider may do tests to see if they are working well enough to take this medicine.

High Potassium Level (Hyperkalemia). Amiloride should not be taken if your blood potassium level is high. Your health care provider will likely check your potassium level before starting amiloride and during treatment.  It is very important to keep all appointments where your blood potassium levels will be measured.

Salt Substitutes or Potassium Supplements. Salt substitutes containing potassium, potassium supplements, or a high-potassium diet should not be used while taking amiloride unless directed to do so by your health care provider. 

Drug Interactions. Amiloride should not be taken while you are using certain other medicines. Before taking amiloride, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

What should I know about amiloride before using it?

Do not take amiloride unless it has been prescribed to you by a health care provider. Take it as prescribed.

Do not share amiloride with other people, even if they have the same condition as you. It may harm them.

Keep amiloride out of the reach of children.

Take amiloride with food.

Amiloride can affect your electrolyte levels, especially potassium and sodium. It is important to discuss your intake of electrolytes with your health care provider, including potassium in food, drinks, or supplements.

What should I tell my health care provider before using amiloride?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if amiloride is right for you.

In particular, make sure that you discuss any of the following.

Current and Past Health Conditions. Tell your health care provider if you have any of the following.

• Liver problems
• Kidney problems
• A reduced need to pee
• Persistent or severe diarrhea or vomiting, which can lead to dehydration
• Electrolyte problems, especially high potassium
• Abnormal heart rhythm (arrhythmias)

Salt Substitutes or Potassium Supplements. Tell your health care provider if you use any salt substitutes or low-salt milk, which often contain potassium, or if you take any potassium supplements. This information is important for your health care provider to check if amiloride is safe for you to take.

Pregnancy. It is not known if or how amiloride could affect pregnancy or harm a fetus. Tell your health care provider if you are pregnant or plan to become pregnant. Your health care provider will let you know if you should take amiloride while you are pregnant or trying to get pregnant.

Breastfeeding. It is not known if amiloride passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed. Your health care provider will let you know if you should stop breastfeeding or stop amiloride.